PATIENT RELATED RISK FACTORS FOR CAT1

Age

Cancer patients aged ≥65 years old have a greater likelihood of developing VTE compared with younger patients.

Sex

Females are at greater risk for VTE, while male patients are more likely to develop ATE.

Race

In a study conducted by Khorana et al., black patients had the highest rate of VTE (5.1%), followed by whites and Hispanic patients (4.0%). The lowest rates were observed in Asian/Pacific Islander patients (3.3%).

Prior VTE

In cancer patients with a personal history of VTE increases the risk of VTE recurrence by 6- to 7-fold compared with cancer patients with no history of VTE.

Comorbidities

Renal failure, respiratory disease, heart disease, obesity, and acute infection are associated with an increased risk of CAT1. A Charlson Comorbidity Index ≥3, is associated with CAT.

Immobility

Immobility increases the chance of VTE through stasis of the venous blood flow. In one study, bed rest of greater than 3 days was associated with significantly higher rates of VTE.

References

  1. Abdol Razak NB et al. Cancers. 2018. 10, 380.

MAT-GB-2000453 (v5.0) Date of preparation: March 2022