Surgery is a well-known risk factor for VTE

• Cancer surgery increases the risk of postoperative DVT 2-fold and that of fatal PE by >3-fold compared with non-cancer patients

have a strong association with VTE

• Cancer patients have a 6- to 7-fold increased risk of developing chemotherapy-associated thrombosis
• Combination chemotherapy with cisplatin increases thrombotic complications in patients with GI cancers
• Other treatments, such as L-asparganase, thalidomide, lenalidomide, hormonal therapy and erythropoiesis-stimulating agents, have also been reported to increase the risk of VTE

It can affect the result of VTE anticoagulant therapy in cancer patients. Ionizing radiation influences protein C pathway and its thrombomodulin interaction²

• Use of central venous catheters can result in the formation of catheter-related thrombosis, a serious complication that can interrupt chemotherapy, blood products, or intravenous medications¹
• Indwelling CVC can increase risk for developing VTE. Estimated rate of symptomatic catheter-related DVT is between 0.3 and 28%¹